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The first avian influenza A (H7N9) viral infection in humans in Zhejiang Province, China: a death report

null

《医学前沿（英文）》 2013年 第7卷 第3期   页码 333-344 doi: 10.1007/s11684-013-0275-1

摘要：

This study reports the first death caused by a novel avian influenza A (H7N9) virus in Zhejiang Province, China. The patient had chronic hepatitis B and history of exposure to poultry. The patient initially complained of diarrhea and influenza-like symptoms on March 7 and 14 respectively. The disease progressed to severe pneumonia, sustained hypoxia, and coagulation abnormalities. The patient died on March 27 because of respiratory failure, multiple organ failure, and disseminated intravascular coagulation without oseltamivir treatment. This H7N9 virus from Zhejiang is highly similar to isolates obtained from Shanghai, Jiangsu, Anhui, etc. Analysis of hemagglutinin, neuramidinase, and matrix genes indicated that the isolates share the same avian origin, have low virulence, and are sensitive to oseltamivir, but are resistant to adamantine. Only the isolate that caused the fatality exhibited substitution of Q226I in the HA gene, which indicates a potentially enhanced human affinity. The secondary transmission rate was 1.6% (2/125). Only two health workers presented with influenza-like symptoms, and they subsequently tested negative for H7N9 RNA. In conclusion, underlying disease, late diagnosis, and untimely antiviral treatment are possible high-risk factors for infections and death caused by the low-pathogenicity avian influenza A (H7N9). Person-to-person transmission of the H7N9 virus was not detected among close contacts, but such transmission should be investigated in the future. Expanding and enhancing surveillance will help in the early discovery and diagnosis of suspected cases, which will reduce the number of severe cases and deaths.

关键词： avian influenza A (H7N9) virus     epidemiology     contacts     person-to-person transmission    

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复杂系统（产品）集成制造工程的技术研究与应用

夏国洪,李伯虎,唐晓青,朱文海,柴旭东

《中国工程科学》 2005年 第7卷 第9期   页码 49-55

摘要：

基于现代集成制造的理念、方法、技术、工具，结合实践，提出并研究了一种能改善复杂产品研发时间（T）、质量（Q）、成本（C）、服务（S）的系统工程——称为“复杂系统（产品）集成制造工程”（简称COSIME）。阐述了它的内涵、系统框架和技术体系，并给出了其中具有特点的6类关键技术的阶段研究成果，包括基于人制管理及有关先进制造模式的复杂产品集成制造系统的经营管理模式；基于项目管理理念的异地企业间并行工程方法与技术；复杂产品虚拟样机工程方法与技术；基于分布仿真技术的复杂产品概念设计与性能评估系统；复杂产品质量控制与管理系统；基于PLM及网络技术的两种复杂产品全生命周期活动集成制造支撑平台等。

关键词： 复杂系统（产品）集成制造工程     复杂产品虚拟样机工程     网格计算     人制管理    

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基于参考网格的差分眼部外观网络的视线估计 Article

顾菘, 王力翚, 何龙, 何先定, 王建

《工程（英文）》 2021年 第7卷 第6期   页码 777-786 doi: 10.1016/j.eng.2020.08.027

摘要：

人类的视线可以有效地传递人们的意图，因此，视线估计方法是智能制造中意图传递的重要研究内容。很多方法通过分析眼部图像，称为眼部图像片，实现视线方向的回归运算。但是，由于眼部图像存在个体差异，这类方法很难建立一个样本无关模型进行视线估计。在本文中，作者假设人眼的外观差异与视线方向差异有直接联系。基于这个假设，本文利用双眼眼部图像片在不同视线时的图像差异估计相应两种视线的差值，构建了差分眼部外观网络（differential eyes’ appearances network, DEANet），并在公共数据集中进行训练。本文提出的DEANet主要基于孪生神经网络（Siamese neural network, SNNet）构建，包含两个结构相同的网络分支。多流数据分别输入到此孪生神经网络的两个分支中。两个网络分支共享相同的权值，实现眼部图像片的特征提取，然后对特征进行拼接，从而获得视线方向的差异。只要完成了视线方向差异模型的训练，在少量的校准图像片的情况下，就可以对其他样本的视线方向差异进行估计。由于测试阶段包含了被测试者的眼部信息，因此估计精度进一步提高。此外，本文提出的方法还有效地避免了在训练样本相关模型时需要大量数据的问题。本文还提出了一种参考网格策略，以便在测试阶段有效地选择一些参考眼部图像片，将它们作为网络的一部分输入，从而进一步提高估计精度。在公共数据集上的实验表明，本文提出的方法优于当前的方法。

关键词： 视线估计     视线方向差     孪生神经网     跨样本估计     人机协作    

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Choosing configurations of transmission line tower grounding by back flashover probability value

Dmitry KUKLIN

《能源前沿（英文）》 2016年 第10卷 第2期   页码 213-226 doi: 10.1007/s11708-016-0398-6

摘要： There is a considerable number of works devoted to electrical characteristics of grounding. These characteristics are important in general. However, in application to grounding of transmission line towers they are not enough to determine what grounding construction is preferable in some particular case, because these characteristics are calculated or measured apart from the grounded object, and only limited number of current (or voltage) source waveforms is used. This paper indicates reasons in favor of the fact that to choose the optimum design of grounding, the calculation model should include the tower as it is. The probability of back flashover, which provides both qualitative and quantitative estimate of the grounding structure efficiency, can be taken as the criterion for the grounding design. The insulation flashover probability is calculated on the basis of engineering method, which evaluates breakdown strength of insulation for nonstandard waveshapes, and probability data on lightning currents. Different approaches are examined for identifying the back flashover probability, as not only amplitudes but also other parameters can be taken into account. Finite-difference time-domain method is used for calculations of transients. It is found that lightning current waveform can greatly influence calculated back flashover probability value.

关键词： grounding     transmission line tower     back flashover probability     FDTD method    

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Recent transmission of Mycobacterium tuberculosis in China: the implication of molecular epidemiology

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《医学前沿（英文）》 2018年 第12卷 第1期   页码 76-83 doi: 10.1007/s11684-017-0609-5

摘要：

Tuberculosis (TB) has remained an ongoing concern in China. The national scale-up of the Directly Observed Treatment, Short Course (DOTS) program has accelerated the fight against TB in China. Nevertheless, many challenges still remain, including the spread of drug-resistant strains, high disease burden in rural areas, and enormous rural-to-urban migrations. Whether incident active TB represents recent transmission or endogenous reactivation has helped to prioritize the strategies for TB control. Evidence from molecular epidemiology studies has delineated the recent transmission of ( ) strains in many settings. However, the transmission patterns of TB in most areas of China are still not clear. Studies carried out to date could not capture the real burden of recent transmission of the disease in China because of the retrospective study design, incomplete sampling, and use of low-resolution genotyping methods. We reviewed the implementations of molecular epidemiology of TB in China, the estimated disease burden due to recent transmission of strains, the primary transmission of drug-resistant TB, and the evaluation of a feasible genotyping method of strains in circulation.

关键词： tuberculosis     recent transmission     molecular epidemiology     China    

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Antibiotic resistome mostly relates to bacterial taxonomy along a suburban transmission chain

《环境科学与工程前沿（英文）》 2022年 第16卷 第3期 doi: 10.1007/s11783-021-1466-7

摘要：

• The α-diversities of resistome were lower in manure and compost than in soils.

关键词： Antibiotic resistance genes     Resistome     Bacterial taxonomy     Transmission chain    

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Planet position errors in planetary transmission: Effect on load sharing and transmission error

Miguel IGLESIAS, Alfonso FERNáNDEZ, Ana DE-JUAN, Ramón SANCIBRIáN, Pablo GARCíA

《机械工程前沿（英文）》 2013年 第8卷 第1期   页码 80-87 doi: 10.1007/s11465-013-0362-7

摘要：

In this paper an advanced model of spur gear transmissions developed by the authors is used to study the influence of carrier planet pin hole position errors on the behaviour of the transmission. The model, initially conceived for external gear modeling, has been extended with internal meshing features, and thus increasing its capabilities to include planetary transmission modeling. The new features are presented, along with the summary of the model general approach. The parameters and characteristics of the planetary transmission used in the paper are introduced. The influence of carrier planet pin hole position errors on the planet load sharing is studied, and several static cases are given as examples in order to show the ability of the model. Tangential and radial planet pin hole position errors are considered independently, and the effect of the load level is also taken into account. It is also given attention to the effect on the transmission error of the transmission. Two different configurations for the planetary transmission are used, attending to the fixed or floating condition of the sun, and the differences in terms of load sharing ratio are shown.

关键词： gear     planetary     epicyclic     transmission     load sharing     transmission error    

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Eliminating mother-to-child transmission of HBV: progress and challenges in China

Wenzhan Jing, Jue Liu, Min Liu

《医学前沿（英文）》 2020年 第14卷 第1期   页码 21-29 doi: 10.1007/s11684-020-0744-2

摘要： China has the world’s largest burden of hepatitis B virus (HBV) infection, but the country has made considerable progress in preventing its mother-to-child transmission (MTCT) in the past three decades. This feat is made possible due to the high coverage of birth-dose hepatitis B vaccine (HepB,>95%), hepatitis B surface antigen (HBsAg) screening for pregnant women (>99%), and hepatitis B immunoglobulin plus HepB for newborns whose mothers are HBsAg positive (>99%). Studies on the optimal antiviral treatment regimen for pregnant women with high HBV-DNA load have also been conducted. However, China still faces challenges in eliminating MTCT of HBV. The overall HBsAg prevalence among pregnant women is considered an intermediate endemic. The prevalence of HBsAg among pregnant women from remote, rural, or ethnic minority areas is higher than that of the national level because of limited health resources and public health education for HBV. The coverage for maternal and child healthcare and immunization services should be improved, especially in western regions. Integration of current services to prevent MTCT of HBV with other relevant health services can increase the acceptability, efficiency, and coverage of these services, particularly in remote areas and ethnic minority areas. By doing so, progress toward key milestones and targets to eliminate hepatitis B as the main public health threat by 2030 can be achieved.

关键词： hepatitis B virus     mother-to-child transmission     progress     challenge    

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An approach for evaluating the impact of an intermittent renewable energy source on transmission expansion

Rongrit CHATTHAWORN,Surachai CHAITUSANEY

《信息与电子工程前沿（英文）》 2015年 第16卷 第10期   页码 871-882 doi: 10.1631/FITEE.1500049

摘要： We propose a new robust optimization approach to evaluate the impact of an intermittent renewable energy source on transmission expansion planning (TEP). The objective function of TEP is composed of the investment cost of the transmission line and the operating cost of conventional generators. A method to select suitable scenarios representing the intermittent renewable energy generation and loads is proposed to obtain robust expansion planning for all possible scenarios. A meta-heuristic algorithm called adaptive tabu search (ATS) is employed in the proposed TEP. ATS iterates between the main problem, which minimizes the investment and operating costs, and the subproblem, which minimizes the cost of power generation from conventional generators and curtailments of renewable energy generation and loads. The subproblem is solved by nonlinear programming (NLP) based on an interior point method. Moreover, the impact of an intermittent renewable energy source on TEP was evaluated by comparing expansion planning with and without consideration of a renewable energy source. The IEEE Reliability Test System 79 (RTS 79) was used for testing the proposed method and evaluating the impact of an intermittent renewable energy source on TEP. The results show that the proposed robust optimization approach provides a more robust solution than other methods and that the impact of an intermittent renewable energy source on TEP should be considered.

关键词： Adaptive tabu search     Renewable energy generation     Robust optimization     Transmission expansion planning    

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Design and characteristic research of a novel electromechanical-hydraulic hybrid actuator with two transmission

《机械工程前沿（英文）》 2023年 第18卷 第2期 doi: 10.1007/s11465-022-0735-x

摘要： Servo-hydraulic actuators (SHAs) are widely used in mechanical equipment to drive heavy-duty mechanisms. However, their energy efficiency is low, and their motion characteristics are inevitably affected by uncertain nonlinearities. Electromechanical actuators (EMAs) possess superior energy efficiency and motion characteristics. However, they cannot easily drive heavy-duty mechanisms because of weak bearing capacity. This study proposes and designs a novel electromechanical-hydraulic hybrid actuator (EMHA) that integrates the advantages of EMA and SHA. EMHA mainly features two transmission mechanisms. The piston of the hydraulic transmission mechanism and the ball screw pair of the electromechanical transmission mechanism are mechanically fixed together through screw bolts, realizing the integration of two types of transmission mechanisms. The control scheme of the electromechanical transmission mechanism is used for motion control, and the hydraulic transmission mechanism is used for power assistance. Then, the mathematical model, structure, and parameter design of the new EMHA are studied. Finally, the EMHA prototype and test platform are manufactured. The test results prove that the EMHA has good working characteristics and high energy efficiency. Compared with the valve-controlled hydraulic cylinder system, EMHA exhibits a velocity tracking error and energy consumption reduced by 49.7% and 54%, respectively, under the same working conditions.

关键词： electromechanical-hydraulic hybrid actuator (EMHA)     integration     transmission mechanisms     power assistance     energy efficiency     working characteristics    

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Aerosol transmission, an indispensable route of COVID-19 spread: case study of a department-store cluster

《环境科学与工程前沿（英文）》 2021年 第15卷 第3期 doi: 10.1007/s11783-021-1386-6

摘要：

• Aerosol transmission is an indispensable route of COVID-19 spread.

关键词： SARS-CoV-2     COVID-19     Environmental factor     Aerosol transmission     Epidemiologic characteristic    

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Interspecies transmission and evolution of the emerging coronaviruses: perspectives from bat physiology

Baicheng HUANG, Kegong TIAN

《农业科学与工程前沿（英文）》 2020年 第7卷 第2期   页码 218-226 doi: 10.15302/J-FASE-2020324

摘要：

Emergent coronaviruses (CoVs) such as SARS-CoV and MERS-CoV have posed great threats to public health worldwide over the past two decades. Currently, the emergence of SARS-CoV-2 as a pandemic causes greater public health concern. CoV diversity is due to the large size and replication mechanisms of the genomes together with having bats as their optimum natural hosts. The ecological behavior and unique immune characteristics of bats are optimal for the homologous recombination of CoVs. The relationship of spatial structural characteristics of the spike protein, a protein that is critical for recognition by host receptors, in different CoVs may provide evidence in explaining the coevolution of CoVs and their hosts. This information may help to enhance our understanding of CoV evolution and thus provide part of the basis of preparations for any future outbreaks.

关键词： bat     coronavirus     evolution     host receptor     spike protein     transmission    

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Reliability analysis of urban gas transmission and distribution system based on FMEA and correlation

Su LI,Weiguo ZHOU

《能源前沿（英文）》 2014年 第8卷 第4期   页码 443-448 doi: 10.1007/s11708-014-0336-4

摘要： In order to improve the safety management of urban gas transmission and distribution system, failure mode and effects analysis (FMEA) was used to construct the reliability analysis system of the pipeline network. To solve the problem of subjectivity and uncertainty of the multi-expert decision making, the correlation operator was introduced into the calculation of the risk priority number (RPN). Using FMEA along with weight analysis and expert investigation approach, the FMEA evaluation table was given, including five failure modes, risk priority numbers, failure causes and effects, as well as corrective actions. The results show that correlation operator can directly process the linguistic terms and quantify the priority of the risks.

关键词： gas transmission and distribution system     risk evaluation     reliability analysis     failure mode and effects analysis (FMEA)     correlation operator    

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Gray-box modeling and QFT control for precision servo transmission systems

Xiulan BAO, Xuedong CHEN, Xin LUO, Haocheng ZUO

《机械工程前沿（英文）》 2011年 第6卷 第4期   页码 442-448 doi: 10.1007/s11465-011-0242-y

摘要：

Precision servo transmission systems have widely been applied in industrial equipment to achieve high accuracy and high speed motion. However, due to the presence of friction and uncertainty, the characteristics of precision servo transmission systems are variant depends on the working conditions, leading to oscillation and instability in the system performances. In this paper, a grey-box model of the system is established, the model structure derived from the theoretical modeling and the model parameters are obtained by experiments using set membership identification method. This paper proposes two-degrees of freedom (2-DOF) robust position controller for a precision servo transmission system, based on the quantitative feedback theory (QFT), to achieve high accuracy and consistent tracking performance even in presence of considerable system uncertainties and friction disturbances. The results of simulate and experiment validate the effectiveness of the proposed controller.

关键词： precision servo transmission system     modeling     set membership identification     quantitative feedback theory (QFT)     robustness    

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Motion/force transmission indices of parallel manipulators

Xinjun LIU, Chao WU, Fugui XIE

《机械工程前沿（英文）》 2011年 第6卷 第1期   页码 89-91 doi: 10.1007/s11465-011-0215-1

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标题 作者 时间 类型 操作

The first avian influenza A (H7N9) viral infection in humans in Zhejiang Province, China: a death report

null

期刊论文

复杂系统（产品）集成制造工程的技术研究与应用

夏国洪,李伯虎,唐晓青,朱文海,柴旭东

期刊论文

基于参考网格的差分眼部外观网络的视线估计

顾菘, 王力翚, 何龙, 何先定, 王建

期刊论文

Choosing configurations of transmission line tower grounding by back flashover probability value

Dmitry KUKLIN

期刊论文

Recent transmission of Mycobacterium tuberculosis in China: the implication of molecular epidemiology

null

期刊论文

Antibiotic resistome mostly relates to bacterial taxonomy along a suburban transmission chain

期刊论文

Planet position errors in planetary transmission: Effect on load sharing and transmission error

Miguel IGLESIAS, Alfonso FERNáNDEZ, Ana DE-JUAN, Ramón SANCIBRIáN, Pablo GARCíA

期刊论文

Eliminating mother-to-child transmission of HBV: progress and challenges in China

Wenzhan Jing, Jue Liu, Min Liu

期刊论文

An approach for evaluating the impact of an intermittent renewable energy source on transmission expansion

Rongrit CHATTHAWORN,Surachai CHAITUSANEY

期刊论文

Design and characteristic research of a novel electromechanical-hydraulic hybrid actuator with two transmission

期刊论文

Aerosol transmission, an indispensable route of COVID-19 spread: case study of a department-store cluster

期刊论文

Interspecies transmission and evolution of the emerging coronaviruses: perspectives from bat physiology

Baicheng HUANG, Kegong TIAN

期刊论文

Reliability analysis of urban gas transmission and distribution system based on FMEA and correlation

Su LI,Weiguo ZHOU

期刊论文

Gray-box modeling and QFT control for precision servo transmission systems

Xiulan BAO, Xuedong CHEN, Xin LUO, Haocheng ZUO

期刊论文

Motion/force transmission indices of parallel manipulators

Xinjun LIU, Chao WU, Fugui XIE

期刊论文